Type 2 diabetes in youth: are there racial differences in β-cell responsiveness relative to insulin sensitivity?
نویسندگان
چکیده
منابع مشابه
Measuring β-Cell Function Relative to Insulin Sensitivity in Youth
OBJECTIVE To compare β-cell function relative to insulin sensitivity, disposition index (DI), calculated from two clamps (2cDI, insulin sensitivity from the hyperinsulinemic-euglycemic clamp and first-phase insulin from the hyperglycemic clamp) with the DI calculated from the hyperglycemic clamp alone (hcDI). RESEARCH DESIGN AND METHODS Complete data from hyperglycemic and hyperinsulinemic-eu...
متن کامل25-Hydroxyvitamin D concentrations and in vivo insulin sensitivity and β-cell function relative to insulin sensitivity in black and white youth. Diabetes Care 2012;35:627–633
D concentrations and in vivo insulin sensitivity and b-cell function relative to insulin sensitivity in black and white youth. In the print version of the article listed above, in the " Biochemical Measurements " section, the sentence " The intrassay and interassay coefficients of variation were 8 ng/mL and 10 ng/mL, respectively " should read as follows: " The intraassay and interassay coeffic...
متن کاملFactors Affecting Insulin Compliance in Patients with Type 2 Diabetes in South Iran, 2017: We Are Faced with Insulin Phobia
Background: Many patients with type 2 diabetes are uncontrolled on maximum oral treatment. The early introduction of insulin can lower diabetes-related complications. This study aimed to evaluate type 2 diabetes patients’ demographic characteristics, clinical factors, and attitude toward insulin therapy initiation. Methods: In the present cross-sectional study, 457 patients were selected from 1...
متن کامل25-Hydroxyvitamin D Concentrations and In Vivo Insulin Sensitivity and β-Cell Function Relative to Insulin Sensitivity in Black and White Youth
OBJECTIVE To examine the relationships between plasma 25-hydroxyvitamin D [25(OH)D] and in vivo insulin sensitivity and β-cell function relative to insulin sensitivity, disposition index (DI), in black and white youth. RESEARCH DESIGN AND METHODS Plasma 25(OH)D concentrations were analyzed in banked specimens in healthy youth aged 8 to 18 years who had existing data on hyperinsulinemic-euglyc...
متن کاملβ‐Cell failure in type 2 diabetes
Type 2 diabetic patients are insulin resistant as a result of obesity and a sedentary lifestyle. Nevertheless, it has been known for the past five decades that insulin response to nutrients is markedly diminished in type 2 diabetes. There is now a consensus that impaired glucose regulation cannot develop without insulin deficiency. First-phase insulin response to glucose is lost very early in t...
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ژورنال
عنوان ژورنال: Pediatric Diabetes
سال: 2011
ISSN: 1399-543X
DOI: 10.1111/j.1399-5448.2011.00820.x